(l) Ephedrine Sulfate USP
   
Molecular Formula : C20H30N2O2. H2SO4
Molecular Weight : 428.55
CAS No. : [134-72-5]
Chemical Name :
1. (1R,2S)-2-Methylamino-1-phenyl propan-1-ol, Sulfate.
2. Benzenemethanol, ?-[1-(methylamino)ethyl]-, [R-(R*,S*)], Sulfate (2:1) salt.
Specifications :
1. Description : Colourless crystals or white crystalline powder
2. Identification : a) Infrared spectrum of sample is concordant with the
reference spectrum.
b) A solution of sample responds to test for sulfate
3. Solubility : Freely soluble in water.
4. Specific rotation : Between - 30.5° and - 32.5° ( 5 % solution in water )
5. Acidity & alkalinity : NMT 0.1 ml of 0.02 N H2SO4 or NMT 0.20 ml of 0.02 N NaOH solution.
6. Chloride : NMT 0.14 %
7. Ordinary impurities : NMT 2.0 %
8. Residue on ignition : NMT 0.1 %
9. Loss on drying : NMT 0.5 %
10. Organic volatile impurities : Must pass the test
11. Assay : Between 98.0 % and 101.0 % ( dry basis )
Therapeutic indications: Bronchodilator
Packing : Packed in double lined polyethylene bags in 25 kg fiber drums.
Storage : Store below 35°C.